RPS27

Across TCGA pan-cancer cohorts, RPS27 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RPS27 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RPS27 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RPS27 expression acts as an unfavorable survival marker, although some lineages such as LUAD and UCEC show a favorable association.

LUAD, CCRCC, and UCEC are the cancer types where RPS27 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	II,III,IV	0.649	0.208	.003	23	view →
CCRCC	OS	Median	All	0.888	1.000	.003	17	view →
UCEC	DFS	Tertile	III,IV	1.000	0.409	.016	8	view →
HNSC	OS	Median	All	1.000	0.449	.023	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RPS27–LUAD (DFS)

Open the LUAD breakdown →