RPS25

Across TCGA patient cohorts, RPS25 protein abundance is significantly associated with the RNA expression of many other genes, with 12,682 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RPS25-associated genes across cancer lineages are SERINC1, LYVE1, and N4BP2L1. Each is linked with RPS25 in more than 6 cancer types. Because this analysis shows association rather than direction, both RPS25-to-partner and partner-to-RPS25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPS25 versus SERINC1 in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS25→partner) and Y-score (partner→RPS25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SERINC1 →	-0.774	-0.359	<.001	.001	3	7
OV	LYVE1 →	-1.558	-0.619	<.001	<.001	2	7
HNSC	N4BP2L1 →	-0.658	-0.278	.002	.003	3	6
LSCC	TNFSF12 →	-0.593	-0.301	<.001	<.001	3	6
BRCA	GPIHBP1 →	-0.960	-0.304	<.001	.002	3	6
OV	NCOA7 →	-0.700	-0.420	.003	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,682 associations by consensus.

RPS25 vs SERINC1 — BRCA

Explore this scatter interactively →