RPS25

Across TCGA patient cohorts, RPS25 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. CESC shows the largest number of these associations.

The most reproducible RPS25-associated genes across cancer lineages are RPL30P13, LINC02530, and LINC01049. Each is linked with RPS25 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS25-to-partner and partner-to-RPS25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL30P13 grouped by RPS25-low versus RPS25-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS25→partner) and Y-score (partner→RPS25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RPL30P13 →	+0.149	+4.705	<.001	.003	3	2
CESC	LINC02530 →	+0.090	+4.234	<.001	.008	3	1
CESC	LINC01049 →	+0.431	+4.539	<.001	.008	3	1
CESC	MTND6P12 →	+0.084	+4.539	<.001	.008	3	1
CESC	SOCS5P3 →	+0.031	+4.503	.001	.005	3	1
CESC	LINC01519 →	+0.030	+4.669	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

RPL30P13 by RPS25 expression — CESC

Explore this box plot interactively →