RPS24P21

Across TCGA pan-cancer cohorts, RPS24P21 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPS24P21’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where RPS24P21 RNA is repressed in tumor relative to normal tissue. In most cancer types RPS24P21 is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.

KIRP, COAD, and KIRC are the cancer types where RPS24P21 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS24P21 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	III,IV	−0.174	.003	6	view →
COAD	Female	II,III,IV	+0.241	.002	4	view →
KIRC	All	II,III,IV	−0.048	.026	4	view →
KICH	All	All	−0.037	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RPS24P21–KIRP

Open the KIRP breakdown →