Across TCGA pan-cancer cohorts, RPS24P1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of RPS24P1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPS24P1 RNA is repressed in tumor relative to normal tissue. In most cancer types RPS24P1 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.
KIRC, KIRP, and ESCA are the cancer types where RPS24P1 tumor–normal differential expression is most reproducible.