RPS24

Across TCGA pan-cancer cohorts, RPS24 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RPS24 data layer compared with 27 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RPS24 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPS24 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where RPS24 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	III,IV	0.243	0.623	.004	29	view →
LUAD	DFS	Quartile	III,IV	0.930	0.372	.006	14	view →
LSCC	DFS	Quartile	II,III,IV	0.903	0.570	.012	6	view →
PDAC	OS	Tertile	IV	0.231	0.905	.024	6	view →
HNSC	DFS	Tertile	All	0.737	1.000	.036	4	view →
GBM	DFS	Tertile	All	0.697	0.846	.033	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RPS24–CCRCC (DFS)

Open the CCRCC breakdown →