RPS24

Across TCGA patient cohorts, RPS24 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPS24-associated genes across cancer lineages are Notch1, PCNA, and STAT3_pY705. Each is linked with RPS24 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS24-to-partner and partner-to-RPS24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by RPS24-low versus RPS24-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS24→partner) and Y-score (partner→RPS24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.148	+3.183	.015	.009	3	1
UCEC	PCNA →	+0.232	+2.999	.014	.035	3	1
UCEC	STAT3_pY705 →	-0.318	-2.115	.005	.019	3	1
UCEC	VHL →	-0.916	-3.584	.001	.002	3	1
UCEC	ATM →	-0.666	-3.571	<.001	.002	3	1
UCEC	Chk2_pT68 →	-0.201	-3.433	.013	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Notch1 by RPS24 expression — UCEC

Explore this box plot interactively →