RPS23P4

Across TCGA pan-cancer cohorts, RPS23P4 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPS23P4’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPS23P4 RNA is repressed in tumor relative to normal tissue. In most cancer types RPS23P4 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and PRAD are the cancer types where RPS23P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS23P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.210	<.001	8	view →
KIRP	All	All	−0.142	.003	4	view →
PRAD	All	All	−0.096	.005	2	view →
BLCA	Female	IV	+0.953	.002	1	view →
KICH	All	All	−0.183	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RPS23P4–KIRC

Open the KIRC breakdown →