Across TCGA pan-cancer cohorts, RPS23 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated RPS23 data layer compared with 23 for mass-spec protein and 6 for mass-spec protein.
The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher RPS23 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RPS23 expression acts as an unfavorable survival marker.
CESC and LUAD are the cancer types where RPS23 Mutation most reproducibly stratifies survival.