Across TCGA patient cohorts, RPS23 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. COAD shows the largest number of these associations.

The most reproducible RPS23-associated genes across cancer lineages are PCNPP2, BMS1P9, and RNU6-661P. Each is linked with RPS23 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS23-to-partner and partner-to-RPS23 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS23→partner) and Y-score (partner→RPS23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PCNPP2 →	+0.144	+5.332	.002	.002	3	2
COAD	BMS1P9 →	+0.217	+4.437	<.001	.002	3	1
COAD	RNU6-661P →	+0.492	+4.666	<.001	.005	3	1
COAD	RNU6-444P →	+1.340	+4.219	<.001	.003	3	1
COAD	MIR320C2 →	+0.784	+4.666	<.001	.005	3	1
COAD	RNU6-1254P →	+0.933	+4.126	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

RPS23 survival (RNA) · tumor vs normal (RNA) · all RPS23 data types