Across TCGA pan-cancer cohorts, RPS21P8 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of RPS21P8’s most consistent transcriptional readouts.
The strongest signal is observed in rectum adenocarcinoma (READ), where RPS21P8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS21P8 is over-expressed in tumor.
READ are the cancer types where RPS21P8 tumor–normal differential expression is most reproducible.