Across TCGA pan-cancer cohorts, RPS21 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated RPS21 data layer compared with 21 for mass-spec protein and 6 for mass-spec protein.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RPS21 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RPS21 expression acts as an unfavorable survival marker.
UCEC are the cancer types where RPS21 Mutation most reproducibly stratifies survival.