RPS20

Across TCGA pan-cancer cohorts, RPS20 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated RPS20 data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RPS20 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RPS20 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

HNSC, CCRCC, and UCEC are the cancer types where RPS20 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	1.000	0.903	.004	31	view →
CCRCC	OS	Tertile	III,IV	0.538	0.842	.005	20	view →
UCEC	DFS	Tertile	III,IV	0.398	1.000	.012	20	view →
GBM	DFS	Quartile	All	0.562	0.866	<.001	19	view →
LSCC	DFS	Tertile	II,III,IV	0.929	0.701	.014	14	view →
PDAC	DFS	Median	II,III,IV	0.462	0.272	.016	11	view →
LUAD	DFS	Quartile	All	0.976	0.858	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RPS20–HNSC (DFS)

Open the HNSC breakdown →