RPS2

Across TCGA pan-cancer cohorts, RPS2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RPS2 data layer compared with 27 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RPS2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RPS2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

CCRCC, GBM, and HNSC are the cancer types where RPS2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.769	0.914	.013	17	view →
GBM	DFS	Quartile	All	0.611	0.848	.002	14	view →
HNSC	OS	Tertile	III,IV	0.794	0.537	.017	11	view →
LSCC	DFS	Median	II,III,IV	0.844	0.569	.009	8	view →
LUAD	DFS	Tertile	All	0.958	0.840	.014	7	view →
PDAC	DFS	Tertile	IV	0.228	0.934	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RPS2–CCRCC (OS)

Open the CCRCC breakdown →