RPS2

Across TCGA patient cohorts, RPS2 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPS2-associated genes across cancer lineages are p62 Lck ligand, Ku80, and p27. Each is linked with RPS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS2-to-partner and partner-to-RPS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p62 Lck ligand grouped by RPS2-low versus RPS2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS2→partner) and Y-score (partner→RPS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.452	+3.179	.005	.010	3	2
UCEC	Ku80 →	+0.247	+2.335	.037	.020	3	1
UCEC	p27 →	+0.314	+2.321	.004	.034	3	1
UCEC	YAP →	+0.162	+3.009	.031	.019	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

p62 Lck ligand by RPS2 expression — UCEC

Explore this box plot interactively →