RPS19

Across TCGA patient cohorts, RPS19 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPS19-associated genes across cancer lineages are EIF3JP1, MIR6761, and LINC01338. Each is linked with RPS19 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS19-to-partner and partner-to-RPS19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EIF3JP1 grouped by RPS19-low versus RPS19-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS19→partner) and Y-score (partner→RPS19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EIF3JP1 →	+0.236	+3.105	.001	.005	3	2
UCEC	MIR6761 →	+0.644	+2.995	.001	.005	3	1
UCEC	LINC01338 →	+0.488	+2.993	<.001	.006	3	1
CESC	RPS27P12 →	+0.261	+5.969	<.001	.002	3	1
CESC	RN7SL616P →	+0.183	+6.144	<.001	.001	3	1
UCEC	MYRF-AS1 →	+0.158	+3.767	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

EIF3JP1 by RPS19 expression — UCEC

Explore this box plot interactively →