Across TCGA pan-cancer cohorts, RPS18P1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPS18P1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where RPS18P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS18P1 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

COAD, LUSC, and KIRC are the cancer types where RPS18P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS18P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.802	<.001	6	view →
LUSC	All	All	−0.191	<.001	5	view →
KIRC	All	All	+0.036	.003	2	view →
HNSC	Female	IV	+0.075	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RPS18P1 RNA expression & survival · all RPS18P1 data types