RPS18

Across TCGA patient cohorts, RPS18 mutation is significantly associated with the RNA expression of many other genes, with 86 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible RPS18-associated genes across cancer lineages are RNA5SP419, RNA5SP303, and RNA5SP416. Each is linked with RPS18 in more than 2 cancer types. Because this analysis shows association rather than direction, both RPS18-to-partner and partner-to-RPS18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by RPS18-low versus RPS18-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS18→partner) and Y-score (partner→RPS18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+1.127	+3.398	<.001	.001	3	3
UCEC	RNA5SP303 →	+0.376	+3.358	<.001	.006	3	2
UCEC	RNA5SP416 →	+0.886	+2.902	<.001	.006	3	2
UCEC	RNA5SP421 →	+1.474	+2.925	<.001	.003	3	2
UCEC	RNA5SP420 →	+1.165	+3.289	<.001	.001	3	2
UCEC	RNA5SP415 →	+1.138	+3.810	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 86 associations by consensus.

RNA5SP419 by RPS18 expression — UCEC

Explore this box plot interactively →