Across TCGA pan-cancer cohorts, RPS17P13 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of RPS17P13’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where RPS17P13 RNA is repressed in tumor relative to normal tissue. In most cancer types RPS17P13 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA are the cancer types where RPS17P13 tumor–normal differential expression is most reproducible.