RPS16

Across TCGA patient cohorts, RPS16 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPS16-associated genes across cancer lineages are Caspase-7-cleavedD198, TSC1, and c-Jun_pS73. Each is linked with RPS16 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS16-to-partner and partner-to-RPS16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by RPS16-low versus RPS16-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS16→partner) and Y-score (partner→RPS16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.899	+2.827	.003	.035	3	2
UCEC	TSC1 →	-0.214	-2.960	.017	.035	3	1
UCEC	c-Jun_pS73 →	-0.194	-3.321	.020	.010	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Caspase-7-cleavedD198 by RPS16 expression — UCEC

Explore this box plot interactively →