Across TCGA pan-cancer cohorts, RPS15AP5 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPS15AP5’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where RPS15AP5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS15AP5 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
COAD, THCA, and LIHC are the cancer types where RPS15AP5 tumor–normal differential expression is most reproducible.