RPS15AP16

Across TCGA pan-cancer cohorts, RPS15AP16 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RPS15AP16 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RPS15AP16 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPS15AP16 expression acts as an unfavorable survival marker, although some lineages such as UCS and DLBC show a favorable association.

UCEC, UCS, and MESO are the cancer types where RPS15AP16 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	III,IV	0.387	0.679	<.001	124	view →
UCS	OS	Tertile	II,III,IV	0.831	0.194	<.001	90	view →
MESO	DFS	Tertile	II,III,IV	0.302	0.601	<.001	67	view →
LUSC	DFS	Median	III,IV	0.164	0.809	<.001	38	view →
KIRC	DFS	Median	II,III,IV	0.444	0.609	.001	36	view →
THCA	DFS	Median	III,IV	0.861	0.970	.002	29	view →
COAD	OS	Median	All	0.741	0.857	<.001	19	view →
READ	DFS	Median	II,III,IV	0.540	0.888	.005	19	view →
DLBC	DFS	Tertile	II,III,IV	0.956	0.520	.012	15	view →
LAML	DFS	Tertile	All	0.681	0.420	.023	14	view →
KICH	DFS	Median	III,IV	0.306	0.857	.013	7	view →
LIHC	DFS	Median	All	0.238	0.356	.009	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RPS15AP16–UCEC (DFS)

Open the UCEC breakdown →