Across TCGA pan-cancer cohorts, RPS15AP15 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of RPS15AP15’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RPS15AP15 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS15AP15 is over-expressed in tumor, although a few such as PAAD and ESCA show the opposite, repressed pattern.

HNSC, PAAD, and ESCA are the cancer types where RPS15AP15 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS15AP15 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.097	.020	5	view →
PAAD	Male	All	−0.295	.007	2	view →
ESCA	All	II,III,IV	−0.210	.002	2	view →
BRCA	All	II,III,IV	+0.072	.027	2	view →
CHOL	All	All	+0.204	.016	1	view →
THCA	All	All	−0.060	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: RPS15AP15 RNA expression & survival · all RPS15AP15 data types