RPS15

Across TCGA pan-cancer cohorts, RPS15 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RPS15 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RPS15 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RPS15 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

HNSC, PDAC, and LUAD are the cancer types where RPS15 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	III,IV	0.920	0.739	.027	16	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	9	view →
LUAD	DFS	Tertile	All	0.994	0.838	.008	6	view →
CCRCC	OS	Tertile	IV	0.109	0.789	.036	6	view →
GBM	DFS	Tertile	All	0.255	0.425	.019	3	view →
LSCC	DFS	Median	III,IV	0.446	0.836	.033	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RPS15–HNSC (DFS)

Open the HNSC breakdown →