RPS15

Across TCGA patient cohorts, RPS15 mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RPS15-associated genes across cancer lineages are RNU6-374P, RN7SL339P, and RNU6-764P. Each is linked with RPS15 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS15-to-partner and partner-to-RPS15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-374P grouped by RPS15-low versus RPS15-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS15→partner) and Y-score (partner→RPS15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-374P →	+0.392	+7.930	<.001	.008	3	1
UCEC	RN7SL339P →	+0.228	+5.520	.001	<.001	3	1
SKCM	RNU6-764P →	+0.395	+4.594	<.001	.008	3	1
SKCM	RNU6-840P →	+0.536	+4.241	.002	.008	3	1
SKCM	OR11H2 →	+0.036	+4.513	<.001	.009	3	1
SKCM	TUBAP4 →	+0.106	+4.241	.009	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

RNU6-374P by RPS15 expression — LUAD

Explore this box plot interactively →