RPS14

Across TCGA patient cohorts, RPS14 mutation is significantly associated with the RNA expression of many other genes, with 122 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPS14-associated genes across cancer lineages are RNU6-1213P, RPL23AP90, and RNU4-5P. Each is linked with RPS14 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS14-to-partner and partner-to-RPS14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1213P grouped by RPS14-low versus RPS14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS14→partner) and Y-score (partner→RPS14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1213P →	+0.296	+4.292	<.001	.006	3	2
UCEC	RPL23AP90 →	+0.608	+4.226	<.001	<.001	3	1
UCEC	RNU4-5P →	+0.615	+2.850	<.001	.007	3	1
UCEC	RNA5SP414 →	+0.978	+3.255	<.001	.003	3	1
UCEC	RNA5SP411 →	+1.583	+3.130	<.001	.003	3	1
UCEC	RNA5SP412 →	+1.047	+2.967	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 122 associations by consensus.

RNU6-1213P by RPS14 expression — UCEC

Explore this box plot interactively →