RPS13

Across TCGA pan-cancer cohorts, RPS13 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RPS13 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RPS13 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RPS13 expression acts as an unfavorable survival marker, although some lineages such as COAD and UCEC show a favorable association.

CCRCC, COAD, and UCEC are the cancer types where RPS13 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.745	0.972	<.001	24	view →
COAD	DFS	Median	III,IV	1.000	0.838	.036	18	view →
UCEC	OS	Tertile	All	1.000	0.850	.019	14	view →
GBM	DFS	Quartile	All	0.218	0.460	.013	7	view →
HNSC	DFS	Median	III,IV	0.913	0.992	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RPS13–CCRCC (OS)

Open the CCRCC breakdown →