Q-omics provides the consensus-scored RPS12P5 profile across patient tissues and cancer cell-line models. RPS12P5 expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in TGCT. Among the 18 cancer types available for tumor–normal comparison, RPS12P5 is differentially expressed in 2, with the highest sampling consensus in STAD. Additionally, RPS12P5 RNA expression shows 12,063 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight TGCT, STAD, and LSCC as cancer lineages where RPS12P5 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPS12P5 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPS12P5 survival associations across molecular data types. RPS12P5 RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPS12P5 RNA expression–survival associations across cancer types. High RPS12P5 expression shows unfavorable associations in TGCT, ACC, UCEC, PAAD and THCA, but favorable associations in ESCA. The TGCT Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify TGCT as the clearest survival context for RPS12P5 RNA expression.
This table summarizes RPS12P5 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for RPS12P5. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPS12P5 shows lower tumor expression in STAD and THCA. The STAD box plot shows higher RPS12P5 RNA expression in normal versus tumor tissue (log2 FC = −0.181, t-test p = .013).
This table shows molecular features associated with RPS12P5 in patient tissues and cancer cell lines. In patient samples, RPS12P5 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.
