Across TCGA pan-cancer cohorts, RPS12P24 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPS12P24’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where RPS12P24 RNA is repressed in tumor relative to normal tissue. In most cancer types RPS12P24 is over-expressed in tumor, although a few such as STAD and KIRC show the opposite, repressed pattern.
STAD, COAD, and HNSC are the cancer types where RPS12P24 tumor–normal differential expression is most reproducible.