RPS12P18

Across TCGA pan-cancer cohorts, RPS12P18 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RPS12P18’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RPS12P18 RNA is repressed in tumor relative to normal tissue. In most cancer types RPS12P18 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

LUSC, LUAD, and UCEC are the cancer types where RPS12P18 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS12P18 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	III,IV	−0.334	.001	4	view →
LUAD	All	All	−0.205	.002	4	view →
UCEC	All	All	−0.136	.038	2	view →
KIRC	Male	All	+0.036	.018	2	view →
ESCA	Male	All	−0.470	.017	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RPS12P18–LUSC

Open the LUSC breakdown →