Across TCGA pan-cancer cohorts, RPS12P15 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RPS12P15’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where RPS12P15 RNA is repressed in tumor relative to normal tissue. In most cancer types RPS12P15 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.
BRCA and LIHC are the cancer types where RPS12P15 tumor–normal differential expression is most reproducible.