RPS12

Across TCGA cell cohorts, RPS12 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,842 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RPS12-associated GO terms across cancer lineages are Transcription initiation at mitochondrial promoter, Glutaminyl-tRNAGln biosynthesis via transamidation, and Embryonic neurocranium morphogenesis. Each is linked with RPS12 in more than 15 cancer types. Because this analysis shows association rather than direction, both RPS12-to-partner and partner-to-RPS12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation at mitochondrial promoter grouped by RPS12-low versus RPS12-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS12→partner) and Y-score (partner→RPS12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Transcription initiation at mitochondrial promoter →	+0.154	+0.719	.006	.002	2	16
PANCREAS	Glutaminyl-tRNAGln biosynthesis via transamidation →	+0.120	+0.993	<.001	<.001	3	14
LARGE_INTESTINE	Embryonic neurocranium morphogenesis →	+0.161	+0.640	<.001	<.001	3	13
OESOPHAGUS	Formate biosynthetic process →	+0.141	+0.776	.001	<.001	2	13
UPPER_AERODIGESTIVE_TRACT	Spermidine biosynthetic process →	+0.138	+0.862	<.001	<.001	3	12
OVARY	Quinone metabolic process →	+0.079	+0.640	.001	.009	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,842 associations by consensus.

Transcription initiation at mitochondrial promoter by RPS12 expression — LIVER

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