RPS11P1

Across TCGA pan-cancer cohorts, RPS11P1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RPS11P1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RPS11P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS11P1 is over-expressed in tumor, although a few such as COAD and BRCA show the opposite, repressed pattern.

HNSC, LUSC, and COAD are the cancer types where RPS11P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS11P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.093	<.001	10	view →
LUSC	All	All	+0.053	.020	3	view →
COAD	Male	II,III,IV	−0.051	.007	3	view →
BRCA	Female	All	−0.024	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RPS11P1–HNSC

Open the HNSC breakdown →