RPS11

Across TCGA patient cohorts, RPS11 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPS11-associated genes across cancer lineages are CD8+ Tcm, CD8+ Tem, and Adipocytes. Each is linked with RPS11 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS11-to-partner and partner-to-RPS11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tcm grouped by RPS11-low versus RPS11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS11→partner) and Y-score (partner→RPS11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ Tcm →	+0.034	+2.713	.001	.018	3	1
UCEC	CD8+ Tem →	+0.004	+4.896	<.001	.036	3	1
UCEC	Adipocytes →	+0.029	+3.507	.003	.007	3	1
UCEC	Hepatocytes →	+0.012	+2.899	.034	.040	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CD8+ Tcm by RPS11 expression — UCEC

Explore this box plot interactively →