RPS11

Across TCGA cell cohorts, RPS11 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RPS11-associated genes across cancer lineages are BTNL2 and OR12D2. Each is linked with RPS11 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPS11-to-partner and partner-to-RPS11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BTNL2 grouped by RPS11-low versus RPS11-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPS11→partner) and Y-score (partner→RPS11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BTNL2 →	+0.081	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR12D2 →	+0.103	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

BTNL2 by RPS11 expression — LARGE_INTESTINE

Explore this box plot interactively →