RPS10P16

Across TCGA pan-cancer cohorts, RPS10P16 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RPS10P16’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RPS10P16 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RPS10P16 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, HNSC, and LIHC are the cancer types where RPS10P16 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RPS10P16 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.126	.001	7	view →
HNSC	Male	All	+0.205	.009	6	view →
LIHC	All	All	+0.151	<.001	6	view →
COAD	All	II,III,IV	+0.510	<.001	5	view →
LUAD	All	All	+0.275	.001	4	view →
CHOL	Male	All	+0.593	<.001	2	view →
KIRP	All	IV	+0.247	.007	2	view →
KICH	Female	All	−0.149	.011	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RPS10P16–KIRC

Open the KIRC breakdown →