RPS10

Across TCGA pan-cancer cohorts, RPS10 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RPS10 data layer compared with 27 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher RPS10 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated RPS10 expression acts as an unfavorable survival marker, although some lineages such as COAD show a favorable association.

GBM, COAD, and HNSC are the cancer types where RPS10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Quartile	All	0.700	0.946	<.001	17	view →
COAD	DFS	Median	III,IV	1.000	0.895	.038	12	view →
HNSC	DFS	Quartile	III,IV	0.661	0.932	.004	11	view →
LUAD	OS	Tertile	III,IV	0.342	0.821	.005	11	view →
CCRCC	DFS	Quartile	III,IV	0.140	0.887	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RPS10–GBM (OS)

Open the GBM breakdown →