RPRML

Across TCGA patient cohorts, RPRML RNA expression is significantly associated with the protein abundance of many other proteins, with 9,619 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPRML-associated proteins across cancer lineages are GCC2, YIF1A, and CACNA2D1. Each is linked with RPRML in more than 2 cancer types. Because this analysis shows association rather than direction, both RPRML-to-partner and partner-to-RPRML results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPRML versus GCC2 in COAD, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RPRML→partner) and Y-score (partner→RPRML) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GCC2 →	-0.258	-0.180	<.001	.001	3	3
BRCA	YIF1A →	-0.304	-0.266	.004	.002	3	3
GBM	CACNA2D1 →	+0.693	+0.984	<.001	<.001	3	3
GBM	SH2D3C_S346 →	+0.610	+0.787	<.001	<.001	3	2
LSCC	SIK3_S915 →	-0.552	-0.115	.009	.004	3	2
LSCC	IRAK2_S144 →	-0.505	-0.191	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,619 associations by consensus.

RPRML vs GCC2 — COAD

Explore this scatter interactively →