RPRD1A

Across TCGA cell cohorts, RPRD1A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,149 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RPRD1A-associated GO terms across cancer lineages are Host-mediated activation of viral transcription, Positive regulation of cilium assembly, and Positive regulation of DNA metabolic process. Each is linked with RPRD1A in more than 16 cancer types. Because this analysis shows association rather than direction, both RPRD1A-to-partner and partner-to-RPRD1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Host-mediated activation of viral transcription grouped by RPRD1A-low versus RPRD1A-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPRD1A→partner) and Y-score (partner→RPRD1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Host-mediated activation of viral transcription →	+0.146	+0.911	<.001	<.001	3	17
LARGE_INTESTINE	Positive regulation of cilium assembly →	+0.095	+0.950	<.001	<.001	3	15
BONE	Positive regulation of DNA metabolic process →	+0.086	+0.839	.001	.001	3	15
SOFT_TISSUE	Microtubule organizing center organization →	+0.082	+0.919	<.001	<.001	3	15
SOFT_TISSUE	Centrosome duplication →	+0.098	+0.802	<.001	<.001	3	15
LUNG_SCLC	Regulation of microtubule polymerization or depolymerization →	+0.120	+0.887	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,149 associations by consensus.

Host-mediated activation of viral transcription by RPRD1A expression — LUNG_SCLC

Explore this box plot interactively →