RPPH1-3P

Across TCGA pan-cancer cohorts, RPPH1-3P RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated RPPH1-3P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RPPH1-3P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPPH1-3P expression acts as an unfavorable survival marker.

KIRC, SKCM, and COAD are the cancer types where RPPH1-3P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.127	0.619	.008	36	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
COAD	DFS	Tertile	All	0.074	0.781	<.001	18	view →
HNSC	OS	Tertile	All	0.191	0.710	.021	18	view →
LGG	DFS	Tertile	All	0.664	0.848	.024	12	view →
SARC	DFS	Tertile	All	0.148	0.594	.016	9	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RPPH1-3P–KIRC (DFS)

Open the KIRC breakdown →