RPP40P1

Across TCGA pan-cancer cohorts, RPP40P1 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RPP40P1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RPP40P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RPP40P1 expression acts as an unfavorable survival marker.

UCEC, THCA, and GBM are the cancer types where RPP40P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.761	0.901	.004	78	view →
THCA	OS	Tertile	All	0.709	0.983	<.001	72	view →
GBM	OS	Tertile	All	0.030	0.416	<.001	36	view →
LAML	DFS	Tertile	All	0.028	0.583	.001	18	view →
LGG	OS	Tertile	All	0.498	0.834	.015	12	view →
BLCA	DFS	Tertile	III,IV	0.159	0.572	.036	9	view →
BRCA	OS	Tertile	All	0.219	0.580	.031	6	view →
STAD	DFS	Tertile	All	0.452	0.724	.041	3	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RPP40P1–UCEC (DFS)

Open the UCEC breakdown →