RPP25L

Across TCGA cell cohorts, RPP25L RNA expression is significantly associated with the go_rna of many other GO terms, with 2,562 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RPP25L-associated GO terms across cancer lineages are Acrosomal vesicle exocytosis, Dense core granule priming, and tRNA methylation. Each is linked with RPP25L in more than 7 cancer types. Because this analysis shows association rather than direction, both RPP25L-to-partner and partner-to-RPP25L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Acrosomal vesicle exocytosis grouped by RPP25L-low versus RPP25L-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPP25L→partner) and Y-score (partner→RPP25L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Acrosomal vesicle exocytosis →	+1.043	+0.765	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Dense core granule priming →	+1.043	+0.879	<.001	.003	3	8
LUNG_NSCLC_LUSC	tRNA methylation →	+0.062	+1.299	<.001	<.001	3	7
BREAST	Purine nucleoside monophosphate biosynthetic process →	+0.069	+0.484	.002	.003	3	7
SKIN	Purine ribonucleoside monophosphate biosynthetic process →	+0.085	+0.801	.002	.001	2	8
OVARY	AMP biosynthetic process →	+0.106	+0.838	.004	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,562 associations by consensus.

Acrosomal vesicle exocytosis by RPP25L expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →