RPP25L

Across TCGA cell cohorts, RPP25L mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RPP25L-associated genes across cancer lineages are OR51T1, GSG1L2, and BTNL2. Each is linked with RPP25L in more than 1 cancer types. Because this analysis shows association rather than direction, both RPP25L-to-partner and partner-to-RPP25L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51T1 grouped by RPP25L-low versus RPP25L-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPP25L→partner) and Y-score (partner→RPP25L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR51T1 →	+0.071	+4.922	<.001	.009	3	1
BLOOD_Leukemia	GSG1L2 →	+0.058	+5.969	<.001	.001	3	1
LARGE_INTESTINE	BTNL2 →	+0.081	+4.415	<.001	.007	3	1
LARGE_INTESTINE	TEX53 →	+0.134	+4.684	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR51T1 by RPP25L expression — BLOOD_Leukemia

Explore this box plot interactively →