RPP14

Across TCGA patient cohorts, RPP14 protein abundance is significantly associated with the RNA expression of many other genes, with 11,234 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RPP14-associated genes across cancer lineages are MS4A2, BUB1, and CDCA2. Each is linked with RPP14 in more than 4 cancer types. Because this analysis shows association rather than direction, both RPP14-to-partner and partner-to-RPP14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPP14 versus MS4A2 in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPP14→partner) and Y-score (partner→RPP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MS4A2 →	-0.810	-0.220	<.001	.002	3	5
PDAC	BUB1 →	+0.904	+0.275	<.001	<.001	3	5
PDAC	CDCA2 →	+1.160	+0.282	<.001	<.001	3	5
LSCC	IFFO1 →	-0.647	-0.359	<.001	<.001	3	4
BRCA	FOXM1 →	+1.151	+0.333	<.001	.001	3	4
LSCC	C7 →	-1.694	-0.287	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,234 associations by consensus.

RPP14 vs MS4A2 — BRCA

Explore this scatter interactively →