RPP14

Across TCGA cell cohorts, RPP14 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,859 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RPP14-associated GO terms across cancer lineages are DNA-templated transcription elongation, RNA 5'-end processing, and Regulation of sister chromatid segregation. Each is linked with RPP14 in more than 15 cancer types. Because this analysis shows association rather than direction, both RPP14-to-partner and partner-to-RPP14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription elongation grouped by RPP14-low versus RPP14-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RPP14→partner) and Y-score (partner→RPP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	DNA-templated transcription elongation →	+0.104	+0.587	<.001	.001	3	16
BONE	RNA 5'-end processing →	+0.095	+0.522	.001	.001	3	15
BREAST	Regulation of sister chromatid segregation →	+0.127	+0.683	<.001	<.001	3	14
KIDNEY	Positive regulation of spindle checkpoint →	+0.138	+0.805	<.001	<.001	3	14
KIDNEY	Positive regulation of mitotic cell cycle spindle assembly checkpoint →	+0.138	+0.805	<.001	<.001	3	14
BLOOD_Myeloma	Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.158	+0.801	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,859 associations by consensus.

DNA-templated transcription elongation by RPP14 expression — LIVER

Explore this box plot interactively →