RPN1

Across TCGA patient cohorts, RPN1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,303 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RPN1-associated genes across cancer lineages are CEP68, GPHN, and GARNL3. Each is linked with RPN1 in more than 5 cancer types. Because this analysis shows association rather than direction, both RPN1-to-partner and partner-to-RPN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPN1 versus CEP68 in BRCA, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPN1→partner) and Y-score (partner→RPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CEP68 →	-0.622	-0.464	<.001	<.001	3	6
CCRCC	GPHN →	-0.614	-0.375	.002	<.001	3	5
GBM	GARNL3 →	-0.701	-0.298	<.001	<.001	3	5
UCEC	MAGEH1 →	-1.151	-0.505	<.001	<.001	3	5
UCEC	SUN2 →	-0.735	-0.364	.005	.006	3	4
UCEC	CHRDL1 →	-1.637	-0.448	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,303 associations by consensus.

RPN1 vs CEP68 — BRCA

Explore this scatter interactively →