RPLP2

Across TCGA patient cohorts, RPLP2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,000 significant associations in total. OV shows the largest number of these associations.

The most reproducible RPLP2-associated genes across cancer lineages are TREM1, FCGR2A, and IRAK3. Each is linked with RPLP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both RPLP2-to-partner and partner-to-RPLP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RPLP2 versus TREM1 in COAD, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPLP2→partner) and Y-score (partner→RPLP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TREM1 →	-1.277	-0.267	<.001	<.001	3	6
OV	FCGR2A →	-1.122	-0.280	<.001	.007	3	6
UCEC	IRAK3 →	-1.058	-0.218	<.001	.001	3	6
COAD	RGCC →	-0.623	-0.323	.002	<.001	3	5
LSCC	MEFV →	-0.613	-0.137	<.001	<.001	3	5
OV	EFEMP1 →	-2.118	-0.466	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,000 associations by consensus.

RPLP2 vs TREM1 — COAD

Explore this scatter interactively →