RPLP2

Across TCGA patient cohorts, RPLP2 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPLP2-associated genes across cancer lineages are MTND1P16, KRT8P25, and MAGI1-AS1. Each is linked with RPLP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPLP2-to-partner and partner-to-RPLP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND1P16 grouped by RPLP2-low versus RPLP2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPLP2→partner) and Y-score (partner→RPLP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MTND1P16 →	+0.084	+5.970	<.001	.002	3	1
SKCM	KRT8P25 →	+0.037	+5.097	<.001	.008	3	1
SKCM	MAGI1-AS1 →	+0.085	+5.362	<.001	.005	3	1
SKCM	TRAJ60 →	+0.816	+5.097	<.001	.008	3	1
LUAD	MIR4252 →	+0.637	+5.712	<.001	.003	3	1
UCEC	MIR6877 →	+0.751	+3.463	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

MTND1P16 by RPLP2 expression — SKCM

Explore this box plot interactively →