RPLP0P2

Across TCGA patient cohorts, RPLP0P2 mutation is significantly associated with the RNA expression of many other genes, with 1,303 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPLP0P2-associated genes across cancer lineages are RNU6-142P, RNU6-666P, and UBE2Q2P12. Each is linked with RPLP0P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPLP0P2-to-partner and partner-to-RPLP0P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-142P grouped by RPLP0P2-low versus RPLP0P2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPLP0P2→partner) and Y-score (partner→RPLP0P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-142P →	+0.250	+3.508	<.001	.006	3	2
LUAD	RNU6-666P →	+0.430	+6.315	<.001	.001	3	2
BRCA	UBE2Q2P12 →	+0.263	+4.002	<.001	<.001	3	1
BRCA	RNU6-743P →	+0.340	+4.002	.001	<.001	3	1
BRCA	GPR160P1 →	+0.089	+3.784	.007	.003	3	1
BRCA	TRAV40 →	+0.299	+3.658	.007	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,303 associations by consensus.

RNU6-142P by RPLP0P2 expression — SKCM

Explore this box plot interactively →