RPL9

Across TCGA patient cohorts, RPL9 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RPL9-associated genes across cancer lineages are Shc_pY317, ASNS, and CD49b. Each is linked with RPL9 in more than 1 cancer types. Because this analysis shows association rather than direction, both RPL9-to-partner and partner-to-RPL9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Shc_pY317 grouped by RPL9-low versus RPL9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RPL9→partner) and Y-score (partner→RPL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Shc_pY317 →	-0.174	-3.169	.037	.020	3	1
UCEC	ASNS →	+0.676	+3.169	<.001	.020	3	1
UCEC	CD49b →	-0.397	-3.156	.011	.020	3	1
UCEC	A-Raf_pS299 →	-0.219	-3.000	<.001	.036	2	1
UCEC	p70-S6K_pT389 →	-0.243	-3.169	.019	.020	2	1
UCEC	14-3-3_epsilon →	-0.107	-2.990	.048	.036	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Shc_pY317 by RPL9 expression — UCEC

Explore this box plot interactively →